Transfer printing is a key technique for the fabrication of flexible electronics. Recently, a novel laser-driven non-contact transfer printing approach has been proposed, which has revealed the great potential by expanding the scope of applications. Compared to the conventional contact transfer printing approaches, the new one is relatively independent of the surface properties and preparation of the substrate onto which the objects are transferred. The challenges still exist in laser-driven non-contact transfer printing such as the ablation of the polymeric transfer tool material due to laser-induced high temperature, which restrict the repeated transfers and massively processing schemes. This research project will focus on the novel transfer printing approach through a systematic and intensive study. Based on the thermal mechanics theory, a general theoretical model will be established to explore the mechanism, explain the experimental observations and predict the complex behavior. Analytical and numerical modeling results will be obtained for an evaluation of the effects which are caused by the main factors. The transfer printing process optimization will be carried out, incorporating the structures, dimensions, material properties and thermal loadings. Then an optimized scheme will be proposed and validated by the experiments to control the critical variables in the transfer printing. The research findings will serve as the design tools and provide the theoretical guidance for improving the success rate and efficiency of the laser-driven non-contact transfer printing, and facilitate the development as well as the applications of the approach in the fabrication of flexible electronics.